The scale of the disaster in Mississippi and Louisiana is unimaginable here in the Midwest. It's not a very edifying response, I know, but I can't help being grateful for living in a part of the world where natural phenomena may be inconvenient, but are almost never deadly.
Sorry to bust your bubble, but a tornado struck Xenia, Ohio in 1974. My recollections are scanty, but I believe one town was hit so badly that only the golden arches of the local McDanalds remained standing.
No-one is immune to misfortune.